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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76792 | Sibrotuzumab | BIBH 1,Anti-Human FAP Recombinant Antibody | Others |
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer. | |||
T76830 | Teneliximab | Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819 | TNF |
Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD... | |||
T5183 | AUT1 | Potassium Channel | |
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a). | |||
T78288 | Inclacumab | Anti-Human selectin P Recombinant Antibody | |
Inclacumab, a humanized monoclonal IgG4 antibody (Anti-Human Selectin P Recombinant Antibody), specifically binds to P-selectin with a dissociation constant (Kd) of 9.9 nM. It effectively prevents the interaction between... | |||
T80744 | Zanolimumab | Anti-Human CD4 Recombinant Antibody | |
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody that targets the CD4 molecule and effectively inhibits T-cell receptor (TCR) signal transduction. It is used in the research of rheum... | |||
T2044 | Varespladib | LY315920 | Phospholipase |
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv... | |||
T82858 | Bleselumab | ASKP 1240,Anti-Human CD40 Recombinant Antibody | |
Bleselumab (ASKP 1240), a human anti-CD40 monoclonal antibody (mAb), exhibits high-affinity binding to CD40 (Kd: 0.24 nM) and hinders immune responses by impeding the CD40-CD40L interaction, thereby preventing organ tran... | |||
T81259 | Rontalizumab | RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody | |
Rontalizumab, a humanized IgG1 monoclonal antibody, targets IFN-α and is utilized in research on systemic lupus erythematosus[1]. | |||
T81050 | Talizumab | TNX 901,Anti-Human IgE Fc Recombinant Antibody | |
Talizumab (TNX 901), a humanized IgG1 monoclonal antibody, targets IgE [1]. | |||
T13566 | Bamirastine | TAK-427 | Histamine Receptor |
Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect on allergic skin inflammation. | |||
T23518 | VUF 5574 | Adenosine Receptor | |
VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor. | |||
T4231 | MD2-IN-1 | TLR | |
MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2). | |||
T7369L | Gemigliptin Tartrate(911637-19-9 free base) | LC15-0444 tartrate | Proteasome , DPP-4 |
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit... | |||
T2000 | AM095 | LPA Receptor , LPL Receptor | |
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. | |||
T6022 | LY404039 | pomaglumetad | Glucocorticoid Receptor , GluR |
LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM). | |||
T19669 | SB399885 | SB399885 Hydrochloride,SB 399885,SB399885,SB-399885 | 5-HT Receptor |
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native ... | |||
T50080 | MC2184 | Sirtuin | |
MC2184 is the inhibitor of human recombinant SIRT1. | |||
T9322 | N-Phenylacrylamide | Others | |
N-Phenylacrylamide inhibit human recombinant TGM2 by fluorescent transamidation assay. | |||
T9901 | Adalimumab | TNF | |
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha. | |||
T8590 | 4-(benzyloxy)benzene-1-sulfonamide | Others | |
4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7. |