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Search Results for " human recombinant "

20

Compounds

Cat No. Product Name Synonyms Targets
T76792 Sibrotuzumab BIBH 1,Anti-Human FAP Recombinant Antibody Others
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer.
T76830 Teneliximab Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819 TNF
Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD...
T5183 AUT1 Potassium Channel
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
T78288 Inclacumab Anti-Human selectin P Recombinant Antibody
Inclacumab, a humanized monoclonal IgG4 antibody (Anti-Human Selectin P Recombinant Antibody), specifically binds to P-selectin with a dissociation constant (Kd) of 9.9 nM. It effectively prevents the interaction between...
T80744 Zanolimumab Anti-Human CD4 Recombinant Antibody
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody that targets the CD4 molecule and effectively inhibits T-cell receptor (TCR) signal transduction. It is used in the research of rheum...
T2044 Varespladib LY315920 Phospholipase
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv...
T82858 Bleselumab ASKP 1240,Anti-Human CD40 Recombinant Antibody
Bleselumab (ASKP 1240), a human anti-CD40 monoclonal antibody (mAb), exhibits high-affinity binding to CD40 (Kd: 0.24 nM) and hinders immune responses by impeding the CD40-CD40L interaction, thereby preventing organ tran...
T81259 Rontalizumab RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody
Rontalizumab, a humanized IgG1 monoclonal antibody, targets IFN-α and is utilized in research on systemic lupus erythematosus[1].
T81050 Talizumab TNX 901,Anti-Human IgE Fc Recombinant Antibody
Talizumab (TNX 901), a humanized IgG1 monoclonal antibody, targets IgE [1].
T13566 Bamirastine TAK-427 Histamine Receptor
Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect on allergic skin inflammation.
T23518 VUF 5574 Adenosine Receptor
VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor.
T4231 MD2-IN-1 TLR
MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189  μM for the recombinant human MD2 (rhMD2).
T7369L Gemigliptin Tartrate(911637-19-9 free base) LC15-0444 tartrate Proteasome , DPP-4
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...
T2000 AM095 LPA Receptor , LPL Receptor
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
T6022 LY404039 pomaglumetad Glucocorticoid Receptor , GluR
LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
T19669 SB399885 SB399885 Hydrochloride,SB 399885,SB399885,SB-399885 5-HT Receptor
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native ...
T50080 MC2184 Sirtuin
MC2184 is the inhibitor of human recombinant SIRT1.
T9322 N-Phenylacrylamide Others
N-Phenylacrylamide inhibit human recombinant TGM2 by fluorescent transamidation assay.
T9901 Adalimumab TNF
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
T8590 4-(benzyloxy)benzene-1-sulfonamide Others
4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.
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